BIG Breast International Group
We will find a cure for breast cancer through global research and collaboration.

You make a big difference


VIDEO: Meet Zoë

September 2016

After being successfully treated for ER+ breast cancer, Zoë dreams of having a baby. But the hormonal treatment, which would take about 5 to 10 years, prevents her from becoming a mom.
Watch her testimonial video and learn how you can make a BIG difference.

We need you

We need you

More than anyone else, you know how much research is important and that you are part of the solution.


The Metastatic Breast Cancer GPS programme

Approximately 1 in 3 of all breast cancers will metastasise, meaning the cancer has spread to other parts of the body. Just as a GPS guidance system helps you...

Leaders in the field of breast cancer research


Results of the MINDACT study are available

Results of the MINDACT clinical trial were presented by Dr Piccart at the AACR Annual Meeting 2016 (New Orleans, USA) on 18 April. The aim of MINDACT was to evaluate the added value of a test of 70 genes (Mammaprint®) to the traditional method of assessing the likelihood of breast cancer recurrence for women with node-negative and 1-to-3 node positive breast cancer. The study results will help oncologists decide which of these patients will be able to safely avoid chemotherapy and the side effects that come with it.


Immunotherapy for breast cancer: what does the future hold?

Checkpoint inhibitors make headlines with promising new data in cancer treatment on an almost daily basis, especially in melanoma and lung cancer. But what role are they - and other forms of immunotherapy - expected to play in breast cancer and why does progress appear to be slower than for some other tumours?


Research that has a true impact on practice

Several of BIG's trials are considered to be landmark, introducing particularly innovative designs, contributing to significant breakthroughs, or paving the way towards more personalised treatment of the disease.


BIG means...No borders. No boundaries. Only possibilities.

Discover our 56 breast cancer research groups.

Finding a cure for breast cancer is one of the biggest challenges faced by researchers from around the world.  


Significant progress has been made to improve both the chances of survival and the quality of life of women affected by the disease.  However, breast cancer remains the second most common cancer in the world and is still responsible for too many deaths annually.


By bringing together the top breast cancer experts from around the world to conduct innovative research, BIG has the global reach and expertise required to find a cure. We need to support such critical research to give hope to women affected by this devastating disease, and their families.



Contact us

Breast International Group (BIG)-aisbl Blvd de Waterloo 121 B-1000 Brussels | Belgium VAT BE 0468 176 240